diff --git a/awx/ui/src/screens/InstanceGroup/Instances/InstanceList.js b/awx/ui/src/screens/InstanceGroup/Instances/InstanceList.js
index d4c86af647..5f511a29fd 100644
--- a/awx/ui/src/screens/InstanceGroup/Instances/InstanceList.js
+++ b/awx/ui/src/screens/InstanceGroup/Instances/InstanceList.js
@@ -89,9 +89,14 @@ function InstanceList() {
     useCallback(
       () =>
         Promise.all(
-          selected.map((instance) =>
-            InstanceGroupsAPI.disassociateInstance(instanceGroupId, instance.id)
-          )
+          selected
+            .filter((s) => s.node_type !== 'control')
+            .map((instance) =>
+              InstanceGroupsAPI.disassociateInstance(
+                instanceGroupId,
+                instance.id
+              )
+            )
         ),
       [instanceGroupId, selected]
     ),
@@ -106,9 +111,11 @@ function InstanceList() {
     useCallback(
       async (instancesToAssociate) => {
         await Promise.all(
-          instancesToAssociate.map((instance) =>
-            InstanceGroupsAPI.associateInstance(instanceGroupId, instance.id)
-          )
+          instancesToAssociate
+            .filter((i) => i.node_type !== 'control')
+            .map((instance) =>
+              InstanceGroupsAPI.associateInstance(instanceGroupId, instance.id)
+            )
         );
         fetchInstances();
       },
@@ -186,7 +193,9 @@ function InstanceList() {
                 verifyCannotDisassociate={false}
                 key="disassociate"
                 onDisassociate={handleDisassociate}
-                itemsToDisassociate={selected}
+                itemsToDisassociate={selected.filter(
+                  (s) => s.node_type !== 'control'
+                )}
                 modalTitle={t`Disassociate instance from instance group?`}
               />,
             ]}
diff --git a/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.js b/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.js
index 442f3b464f..d3891e3755 100644
--- a/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.js
+++ b/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.js
@@ -106,9 +106,9 @@ function InstanceListItem({
         <Td
           select={{
             rowIndex,
-            isSelected,
+            isSelected: isSelected && instance.node_type !== 'control',
             onSelect,
-            disable: false,
+            disable: instance.node_type === 'control',
           }}
           dataLabel={t`Selected`}
         />
diff --git a/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.test.js b/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.test.js
index 0b660da15c..681dfd9482 100644
--- a/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.test.js
+++ b/awx/ui/src/screens/InstanceGroup/Instances/InstanceListItem.test.js
@@ -38,6 +38,33 @@ const instance = [
     managed_by_policy: true,
     node_type: 'hybrid',
   },
+  {
+    id: 2,
+    type: 'instance',
+    url: '/api/v2/instances/1/',
+    related: {
+      jobs: '/api/v2/instances/1/jobs/',
+      instance_groups: '/api/v2/instances/1/instance_groups/',
+    },
+    uuid: '00000000-0000-0000-0000-000000000001',
+    hostname: 'awx-control',
+    created: '2020-07-14T19:03:49.000054Z',
+    modified: '2020-08-12T20:08:02.836748Z',
+    capacity_adjustment: '0.40',
+    version: '13.0.0',
+    capacity: 10,
+    consumed_capacity: 0,
+    percent_capacity_remaining: 60.0,
+    jobs_running: 0,
+    jobs_total: 68,
+    cpu: 6,
+    memory: 2087469056,
+    cpu_capacity: 24,
+    mem_capacity: 1,
+    enabled: true,
+    managed_by_policy: true,
+    node_type: 'control',
+  },
 ];
 
 describe('<InstanceListItem/>', () => {
@@ -167,6 +194,24 @@ describe('<InstanceListItem/>', () => {
     );
   });
 
+  test('should disable checkbox', async () => {
+    const onSelect = jest.fn();
+    await act(async () => {
+      wrapper = mountWithContexts(
+        <table>
+          <tbody>
+            <InstanceListItem
+              instance={instance[1]}
+              onSelect={onSelect}
+              fetchInstances={() => {}}
+            />
+          </tbody>
+        </table>
+      );
+    });
+    expect(wrapper.find('Td').first().prop('select').disable).toEqual(true);
+  });
+
   test('should display instance toggle', () => {
     expect(wrapper.find('InstanceToggle').length).toBe(1);
   });